Cabaletta Bio (NASDAQ:CABA – Get Free Report) and Outlook Therapeutics (NASDAQ:OTLK – Get Free Report) are both small-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their institutional ownership, dividends, valuation, risk, profitability, earnings and analyst recommendations.
Profitability
This table compares Cabaletta Bio and Outlook Therapeutics’ net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Cabaletta Bio | N/A | -50.10% | -45.49% |
| Outlook Therapeutics | N/A | N/A | -225.12% |
Institutional and Insider Ownership
11.2% of Outlook Therapeutics shares are owned by institutional investors. 9.9% of Cabaletta Bio shares are owned by company insiders. Comparatively, 4.8% of Outlook Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.
Analyst Recommendations
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Cabaletta Bio | 0 | 1 | 6 | 1 | 3.00 |
| Outlook Therapeutics | 0 | 1 | 4 | 0 | 2.80 |
Cabaletta Bio currently has a consensus target price of $22.71, indicating a potential upside of 1,205.42%. Outlook Therapeutics has a consensus target price of $10.20, indicating a potential upside of 575.50%. Given Cabaletta Bio’s stronger consensus rating and higher probable upside, analysts plainly believe Cabaletta Bio is more favorable than Outlook Therapeutics.
Volatility and Risk
Cabaletta Bio has a beta of 2.58, meaning that its share price is 158% more volatile than the S&P 500. Comparatively, Outlook Therapeutics has a beta of 0.54, meaning that its share price is 46% less volatile than the S&P 500.
Valuation and Earnings
This table compares Cabaletta Bio and Outlook Therapeutics”s gross revenue, earnings per share (EPS) and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Cabaletta Bio | N/A | N/A | -$67.68 million | ($2.15) | -0.81 |
| Outlook Therapeutics | N/A | N/A | -$75.37 million | ($7.42) | -0.20 |
Cabaletta Bio is trading at a lower price-to-earnings ratio than Outlook Therapeutics, indicating that it is currently the more affordable of the two stocks.
Summary
Cabaletta Bio beats Outlook Therapeutics on 9 of the 12 factors compared between the two stocks.
About Cabaletta Bio
Cabaletta Bio, Inc., a clinical-stage biotechnology company, focuses on the discovery and development of engineered T cell therapies for patients with B cell-mediated autoimmune diseases. The company's lead product candidate is CABA-201, a fully human anti-CD19 binder for the treatment of Phase 1/2 clinical trials in dermatomyositis, anti-synthetase syndrome, immune-mediated necrotizing myopathy, lupus nephritis, non-renal systemic lupus erythematosus, systemic sclerosis, and generalized myasthenia gravis. It also develops DSG3-CAART, which is in Phase I/II clinical trial for the treatment of mucosal pemphigus vulgaris; and MuSK-CAART, an investigational cell therapy that is in Phase I/II clinical trial for treating patients with anti- muscle-specific kinase antibody positive myasthenia gravis. It has a collaboration with the University of Pennsylvania and the Children's Hospital of Philadelphia; Nanjing IASO Biotherapeutics Co., Ltd; Oxford Biomedica; and WuXi Advanced Therapies, Inc. The company was formerly known as Tycho Therapeutics, Inc. and changed its name to Cabaletta Bio, Inc. in August 2018. Cabaletta Bio, Inc. was incorporated in 2017 and is headquartered in Philadelphia, Pennsylvania.
About Outlook Therapeutics
Outlook Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company, focuses on developing and commercializing monoclonal antibodies for various ophthalmic indications. Its lead product candidate is ONS-5010, an ophthalmic formulation of bevacizumab product candidate that is in Phase-III clinical trial for the treatment of wet age-related macular degeneration and other retina diseases. Outlook Therapeutics, Inc. has collaboration and license agreements with BioLexis Pte. Ltd. and Zhejiang Huahai Pharmaceutical Co., Ltd. The company was formerly known as Oncobiologics, Inc. and changed its name to Outlook Therapeutics, Inc. in November 2018. Outlook Therapeutics, Inc. was incorporated in 2010 and is based in Iselin, New Jersey.
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